seagen press releases

THIRD QUARTER AND NINE-MONTHS 2022 FINANCIAL RESULTS Revenues: Total revenues for the third quarter and nine months ended September 30, 2022 were $510 million and $1,434 million, respectively, compared to $424 million and $1,145 million for the same periods in 2021. Seagen Inc. (Nasdaq: SGEN) today announced that the phase 3 ECHELON-1 clinical trial demonstrated a statistically significant improvement in overall survival (OS) (p=0.009) in patients with. News Press Releases Seagen Announces Jury Award in Patent Infringement Case Against Daiichi Sankyo SGEN | April 8, 2022 - Jury Upholds Validity of Asserted Claims of the Patent, Finds Willful Infringement and Issues Past Damages Award of $41.82 Million - - Seagen to Request Royalty on Future U.S. Indication and Important Safety Information. The increase in full year 2021 primarily reflected a $200 million upfront payment due under the RemeGen collaboration agreement for disitamab vedotin. Seattle Genetics (SGEN) Reports Q3 Loss, Tops Revenue Estimates Seattle Genetics (SGEN) delivered earnings and revenue surprises of -11.96% and 8.75%, respectively, for the quarter ended September. Bothell, Washington. U.S. Condensed Consolidated Statements of Operations, Shares used in computation of per share amounts - basic, Shares used in computation of per share amounts - diluted, Total liabilities and stockholders equity, View source version on businesswire.com: In HER2CLIMB, Grade 3 laboratory abnormalities reported in 5% of patients who received TUKYSA were: decreased phosphate, increased ALT, decreased potassium, and increased AST. We look forward to working with Seagen to develop potential next generation cancer treatments.. Avenue. Serious adverse reactions in 2% of patients who received TUKYSA were diarrhea (4%), vomiting (2.5%), nausea (2%), abdominal pain (2%), and seizure (2%). Certain statements made in this press release are forward-looking, such as those, among others, relating to the therapeutic potential of LAVA-1223 and the Gammabody platform, including possible efficacy, safety and therapeutic uses, as well as clinical development plans. Many factors, risks and uncertainties may cause differences between current expectations and actual results including, among other things, the timing and results of our research and development programs and preclinical and clinical trials, our ability to obtain regulatory approval for and commercialize our product candidates, our ability to leverage our initial programs to develop additional product candidates using our Gammabody platform, and the failure of LAVAs collaborators to support or advance collaborations or our product candidates. Douglas Maffei, Ph.D. TUKYSA is an oral medicine that is a tyrosine kinase inhibitor of the HER2 protein. Certain statements made in this press release are forward looking, such as those, among others, relating to the therapeutic potential of enfortumab vedotin, including its efficacy, safety and . Forward-looking statements contained in this press release include, but are not limited to, statements about the preclinical data, clinical development and scope of clinical trials, and the potential use of our product candidates to treat various tumor targets. Conferences, Seagen Article. Seagen does not necessarily endorse the organization associated with this link and takes no responsibility for the content contained therein. Non-cash costs include share-based compensation, depreciation and amortization of intangible assets. Earnings Surprises: Which stocks are most likely to rally? Cambridge, Massachusetts, United States. You can unsubscribe to any of the investor alerts you are subscribed to by visiting the unsubscribe section below. LAVA-1223 employs a targeted approach that is designed to amplify natural tumor recognition by directing gamma delta T cells to the EGFR+ tumor to kill target cells and trigger immune activation while minimizing impact to normal antigen-expressing tissue. Certain of the statements made in this press release are forward looking, such as those, among others, relating to the Companys 2022 outlook, including anticipated 2022 revenues, costs and expenses; the Companys potential to achieve the noted development and regulatory milestones in 2022 and in future periods; the Company's pipeline; anticipated activities related to the Companys planned and ongoing clinical trials; the potential for the Companys clinical trials to support further development, regulatory submissions and potential marketing approvals in the U.S. and in other countries; the opportunities for, and the therapeutic and commercial potential of ADCETRIS, PADCEV, TUKYSA, TIVDAK, ladiratuzumab vedotin, disitamab vedotin, the Companys other product candidates and the products and product candidates of its licensees and collaborators; the potential for data from cohort K of the EV-103 trial (together with other data from the EV-103 trial) and/or the MOUNTAINEER trial to support registration under the FDAs accelerated approval pathway; the EC decision-making process with respect to the marketing authorization application (MAA) for PADCEV, including the pause for additional CHMP questions related to severe skin reactions in a French compassionate access program; the Companys global expansion; potential future milestone payments and royalties under the Companys collaborations; as well as other statements that are not historical fact. and bothell, wash., sept. 27, 2022 (globe newswire) -- zai lab limited (nasdaq: zlab; hkex: 9688), a patient-focused, innovative, commercial-stage global biopharmaceutical company, and seagen inc. (nasdaq: sgen), a world leader and pioneer in antibody-drug conjugate (adc) therapies today announced an exclusive Primarily focused on a commercialized drug . You are now leaving Seagen site. 19-06-2022. By providing your email address below, you are providing consent to Seagen to send you the requested Investor Email Alert updates. Senior Vice President, Investor Relations Paris, March 16, 2022. It was approved by the U.S. FDA in April 2020 and by the European Medicines Agency and the UK Medicines and Healthcare Products Regulatory Agency in February 2021. At Seagen, we will not share your information with any third party. - FDA Has Set Action Date of January 19, 2023 - Seagen Inc. (Nasdaq: SGEN) today announced that the U.S. Food and Drug Administration (FDA) has accepted for Priority Review the supplemental New Drug Application (sNDA) seeking accelerated approval for TUKYSA (tucatinib) in combination with trastuzumab for adult patients with HER2-positive colorectal cancer who have received at least one . Adverse reactions led to treatment discontinuation in 6% of patients who received TUKYSA; those occurring in 1% of patients were hepatotoxicity (1.5%) and diarrhea (1%). Track . Oct 2021 - Apr 20227 months. The press release and supporting slides are available on our website in the Investors section, Events . News Press Releases Seagen President, CEO and Chairman Clay Siegall Takes Leave of Absence SGEN | May 9, 2022 Roger Dansey, M.D., Chief Medical Officer, Appointed Interim CEO The Board of Directors of Seagen Inc. (Nasdaq: SGEN) today announced that President, CEO and Chairman Clay Siegall, Ph.D. is on a leave of absence. LAVA-1223 is a potential first-in-class therapy designed specifically to target and activate V9V2 (gamma delta) T cells in the presence of epidermal growth factor receptor (EGFR)-expressing tumor cells. Seagen Inc. (Nasdaq: SGEN), a world leader and pioneer in antibody-drug conjugate (ADC) therapies, and LAVA Therapeutics N.V. (Nasdaq: LVTX), a clinical-stage immuno-oncology company focused on developing its proprietary Gammabody platform of bispecific gamma delta T cell engagers, today announced an exclusive license agreement in which Seagen will work to develop, manufacture and commercialize LAVA-1223. -Total Revenues of $1.6 Billion in 2021, Including 38 Percent Annual Increase in Total Net Product Sales to $1.4 Billion-, -Growth Across Commercial Portfolio of Four Oncology Products-, -ADCETRIS (brentuximab vedotin) Combination Significantly Improves Overall Survival in Newly Diagnosed Patients with Advanced Hodgkin Lymphoma-, -Multiple Key Milestones Anticipated in 2022-. Teplizumab reduces the loss of beta-cell function, which delays . See more . Seagen Contacts For Investors Peggy Pinkston Senior Vice President, Investor Relations (425) 527-4160 ppinkston@seagen.com For Media David Caouette Vice President, Corporate Communications (310) 430-3476 dcaouette@seagen.com Seagen Forward-Looking Statements Collaboration revenues for the fourth quarter and full year 2020 reflected license revenue related to the agreements with Merck for ladiratuzumab vedotin and TUKYSA (see Collaboration and License Agreement Revenues section below). [1] American Cancer Society: Key Statistics for Colorectal Cancer-2022. reported Q3 sales of $510.30 million. Dec 2019 - Jun 20222 years 7 months. TUKYSA is approved in 38 countries. Rare diseases: Article Lupkynis granted approval in Europe . EGFR is a well-validated target that is over-expressed in multiple solid tumor types including colorectal cancer, lung cancer and head and neck cancer. If you experience any issues with this process, please contact us for further assistance. LAVA-1223 is an advanced preclinical asset that utilizes LAVAs proprietary Gammabody technology to target epidermal growth factor receptor (EGFR)-expressing solid tumors. - Seagen to Develop and Commercialize LAVA-1223, a Bispecific T Cell Engager Designed to Target and Activate V9V2 (Gamma Delta) T Cells in the Presence of EGFR-Expressing Solid Tumors . To opt-in for investor email alerts, please enter your email address in the field below and select at least one alert option. You can unsubscribe to any of the investor alerts you are subscribed to by visiting the unsubscribe section below. We're committed to discovering safe and effective solutions to challenging clinical needs. Under the terms of the agreement, Seagen will receive an exclusive global license for LAVA-1223 and pay LAVA $50 million upfront; up to approximately $650 million in potential development, regulatory and commercial milestones; and royalties ranging from the single digits to the mid-teens on future sales. Big M&A rumors continue to swirl round the pharma world this summer, with talk of a Pfizer bid for Global Blood Therapeutics in the offing. After submitting your request, you will receive an activation email to the requested email address. Metastatic patterns and survival outcomes in patients with stage IV colon cancer: A populationbased analysis. Vice President, Corporate Communications Cash and Investments: As of December 31, 2021, Seagen had $2.2 billion in cash and investments. Sanofi and Seagen Inc. (Nasdaq:SGEN) today announced an exclusive collaboration agreement to design, develop, and commercialize antibody-drug conjugates (ADCs) for up to. [2] Wang J., et al. SGEN. [3] Ahcene Djaballah S, Daniel F, Milani A, Ricagno G, Lonardi S. HER2 in Colorectal Cancer: The Long and Winding Road From Negative Predictive Factor to Positive Actionable Target. Under the terms of the agreement, Seagen will receive an exclusive global license for LAVA-1223 and pay LAVA $50 million upfront; up to approximately $650 million in potential development,. Seagen is a global biotechnology company that discovers, develops and commercializes transformative cancer medicines to make a meaningful difference in peoples lives. The increases in 2021 were primarily related to the gross profit share owed to our collaboration partners which were $46.2 million and $162.0 million in the fourth quarter and full year in total, respectively, compared to $32.1 million and $104.6 million for the same periods in 2020. The week in pharma: action, reaction and insight - week to June 17 2022. Find the latest press releases from Seagen Inc. Common Stock (SGEN) at Nasdaq.com. LAVA assumes no obligation to update any forward-looking statements contained herein to reflect any change in expectations, even as new information becomes available. Share-Based compensation, depreciation and amortization of intangible assets SGEN-1.01 % ) 4:00 PM 10/14/22 NASDAQ | $ | To opt-in for investor email alert updates the field below and select at least one alert option metastatic cancer. A meaningful difference in peoples lives this process, please contact us for further assistance opt-in for investor alerts! Call by calling 844-763-8274 ( domestic ) or 412-717-9224 ( international ) diverse of. Maximize the potential of our commercial portfolio through broad clinical development programs that are intended to serve a! 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